Shu-Lin Liu has expertise in bacterial systematics and evolution. He was the first in the world to conduct comparative genomic studies on Salmonella bacteria and uncovered a series of genomic evolutionary events, with findings published in PNAS, Journal of Bacteriology, Molecular Biology and Evolution, etc. He proposed the 3Cs criteria to define natural species of bacteria and put forward the Adopt-Adapt Model of bacterial speciation, which may lead to the origin of pathogenic species. He teaches Microbiology, Genomics, Evolution, and Classic Chinese Literature. He has an adjunct academic position at University of Calgary, Canada, and conducted teaching and research there. As the Dean of College of Pharmacy, Harbin Medical University, he was active in international collaboration and communication activities and organized a broad range of exchange programs with international institutions including University of British Columbia, University of Calgary, Canada, and Purdue University, University of Missouri, Kentucky State University, USA, etc.