Wolfram Brueck
University of Applied Sciences Western Switzerland Valais, Switzerland
Title: Applied Microbes: The good, the bad and the fastidious
Biography
Biography: Wolfram Brueck
Abstract
Assemblies of microorganisms in their various environmental niches harbour a vast metabolic potential. To make use of its specific activity, the targeted identification of particular members of these communities within or outside of its native habitat has been done to facilitate novel processes or functions or to hasten existing ones. Mining this prospective wealth of activity for biotechnology, agriculture, medicine, food microbiology and bioremediation is at the core of applied microbiology. For example, Entotheonella, a microbial marine invertebrate symbiont is assumed to produce an antifungal agent in the Palauan sponge Theonella swinhoei. The same organism, on the other hand may produce an immunosuppressive, neuroprotective, antiproliferative, microtubule-stabilizing and antifungal compound in the Caribbean sponge Discodermia dissoluta. Another example is the use of the shell wastes of marine invertebrates and the chitinolytic machinery of Serratia marcescens in combination with the acid production of Lactobacillus and the proteases of Bacillus cereus, which leads to an environmentally friendlier alternative to traditional production of chitin and chitosan. Additionally, Lactobacillus by itself has been shown to protect from urinary tract infections while its status as probiotic has long been established. Today it is well known that the microbiota composition of our gut influences strongly our health and dysbiosis is a serious risk factor. Targeted intervention of probiotics such as Lactobacillus and Bifidobacterium may counteract the dysbiosis caused by various extrinsic factors during the acquisition of the early microbiota and into adulthood. Microorganisms for the maintenance of our well-being.